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Melanoma Antigen Family H, 1 (MAGEH1) (AA 186-218), (C-Term) antibody

Details for Product No. ABIN390121, Supplier: Log in to see
Antigen
  • MAGEH1
  • APR-1
  • APR1
  • MAGEH
  • 2010107K23Rik
Alternatives
anti-Human Melanoma Antigen Family H, 1 antibody for ELISA
Epitope
AA 186-218, C-Term
19
8
6
5
1
1
Reactivity
Human
42
3
3
Host
Rabbit
35
7
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
30
25
21
6
6
2
Supplier
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Immunogen This MAGEH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-218 AA from the C-terminal region of human MAGEH1.
Clone RB2129
Isotype Ig
Specificity This MAGEH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190~219 amino acids from the C-terminal region of human MAGEH1.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MAGEH1 (MAGEH1 Antibody Abstract)
Background Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGEH1 is not fully elucidated, it may play a role in embryonal development and tumor transformation or aspects of tumor progression.
Synonyms: Melanoma-associated antigen H1, MAGE-H1 antigen, Restin, MAGE-H1 antigen, APR-1, APR1
Molecular Weight 24441 DA
Gene ID 28986
UniProt Q9H213
Research Area Apoptosis/Necrosis, Cancer, Cell Structure
Pathways Neurotrophin Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Melanoma Antigen Family H, 1 (MAGEH1) (AA 186-218), (C-Term) antibody (ABIN390121) The anti-MAGEH1 Pab (ABIN390121) is used in Western blot to detect MAGEH1 in Jurkat c...
Immunohistochemistry (IHC) image for anti-Melanoma Antigen Family H, 1 (MAGEH1) (AA 186-218), (C-Term) antibody (ABIN390121) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-Melanoma Antigen Family H, 1 (MAGEH1) (AA 186-218), (C-Term) antibody (ABIN390121) Western blot analysis of MAGEH1 (arrow) using rabbit polyclonal MAGEH1 Antibody (D201...
Background publications Chomez, De Backer, Bertrand et al.: "An overview of the MAGE gene family with the identification of all human members of the family." in: Cancer research, Vol. 61, Issue 14, pp. 5544-51, 2001 (PubMed).

Zhu, Yan, Zhao et al.: "Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes." in: BioTechniques, Vol. 29, Issue 2, pp. 310-3, 2000 (PubMed).