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MMP15 antibody (Matrix Metallopeptidase 15 (Membrane-inserted)) (AA 165-194)

Details for Product anti-MMP15 Antibody No. ABIN390139, Supplier: Log in to see
Antigen
  • AI503551
  • MT2-MMP
  • MTMMP2
  • SMCP-2
Epitope
AA 165-194, N-Term
33
15
8
7
5
4
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
104
47
21
1
Host
Rabbit
105
12
Clonality (Clone)
Polyclonal ()
Conjugate
This MMP15 antibody is un-conjugated
6
6
5
4
4
4
2
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
83
50
39
21
21
11
7
5
4
1
Supplier
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Immunogen This MMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 AA from the N-terminal region of human MMP15.
Clone RB2029
Isotype Ig
Specificity This MMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MMP15.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MMP15 (MMP15 Antibody Abstract)
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP15 is a member of the membrane-type MMP (MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.
Molecular Weight 75807 DA
Gene ID 4324
NCBI Accession NP_002419
Research Area Stem Cells, Cell Structure, Protein Modifications, Cancer
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MMP15 antibody (Matrix Metallopeptidase 15 (Membrane-inserted)) (AA 165-194) (ABIN390139) The anti-MMP15 N-term Antibody (ABIN390139) is used in Western blot to detect MMP15 i...
Immunohistochemistry (IHC) image for anti-MMP15 antibody (Matrix Metallopeptidase 15 (Membrane-inserted)) (AA 165-194) (ABIN390139) Formalin-fixed and paraffin-embedded human colon carcinoma with MMP15 Antibody (N-ter...
Flow Cytometry (FACS) image for anti-MMP15 antibody (Matrix Metallopeptidase 15 (Membrane-inserted)) (AA 165-194) (ABIN390139) Flow cytometric analysis of WiDr cells using MMP15 Antibody (N-term)(bottom histogram...
Background publications Sato, Tanaka, Takino, Inoue, Seiki: "Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization." in: Genomics, Vol. 39, Issue 3, pp. 412-3, 1997 (PubMed).

Mattei, Roeckel, Olsen, Apte: "Genes of the membrane-type matrix metalloproteinase (MT-MMP) gene family, MMP14, MMP15, and MMP16, localize to human chromosomes 14, 16, and 8, respectively." in: Genomics, Vol. 40, Issue 1, pp. 168-9, 1997 (PubMed).