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Alanine Glyoxylate Aminotransferase (AGXT) (AA 96-125), (Center) antibody

Details for Product No. ABIN390393, Supplier: Log in to see
Antigen
  • AGT
  • AGT1
  • AGXT1
  • PH1
  • SPAT
  • SPT
  • TLH6
  • Agt1
  • Agxt1
  • Spat
Epitope
AA 96-125, Center
37
10
6
3
1
Reactivity
Human
55
15
8
2
Host
Rabbit
26
26
15
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
4
4
4
4
4
4
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
47
26
6
6
6
5
2
1
Supplier
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Immunogen This AGXT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 AA from the Central region of human AGXT.
Clone RB18848
Isotype Ig
Specificity This AGXT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103~133 amino acids from the Center region of human AGXT.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name AGXT (AGXT Antibody Abstract)
Background AGXT is expressed only in the liver and protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification.
Synonyms: Serine--pyruvate aminotransferase, SPT, Alanine--glyoxylate aminotransferase, AGT, SPAT, AGT1, AGXT
Molecular Weight 43010 DA
Gene ID 189
UniProt P21549
Research Area Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Alanine Glyoxylate Aminotransferase (AGXT) (AA 96-125), (Center) antibody (ABIN390393) Western blot analysis of AGXT Antibody (Center) (ABIN390393) in HepG2 cell line lysat...
Immunohistochemistry (IHC) image for anti-Alanine Glyoxylate Aminotransferase (AGXT) (AA 96-125), (Center) antibody (ABIN390393) AGXT Antibody (Center) (ABIN390393) IHC analysis in formalin fixed and paraffin embed...
Background publications Cellini, Montioli, Paiardini et al.: "Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation." in: The Journal of biological chemistry, Vol. 284, Issue 13, pp. 8349-58, 2009 (PubMed).

Bertoldi, Cellini, Paiardini et al.: "Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis." in: Biochimica et biophysica acta, Vol. 1784, Issue 9, pp. 1356-62, 2008 (PubMed).