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Valosin Containing Protein (vcp) (AA 726-755), (C-Term) antibody

Details for Product No. ABIN390907, Supplier: Log in to see
Antigen
  • ALS14
  • IBMPFD
  • TERA
  • p97
  • 3110001E05
  • CDC48
  • p97/VCP
  • p93
  • wu:fd16d05
  • wu:fj63d11
  • valosin containing protein
  • valosin-containing protein
  • VCP
  • Bm1_56585
  • LOC100136246
  • Vcp
  • vcp
Epitope
AA 726-755, C-Term
30
6
6
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
144
80
58
9
9
9
7
7
7
4
4
4
4
4
2
1
1
1
1
1
1
1
1
Host
Rabbit
89
58
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
5
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
133
46
45
35
34
28
27
24
7
4
2
2
1
1
1
1
1
Options
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Immunogen This VCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 726-755 AA from the C-terminal region of human VCP.
Clone RB21276
Isotype Ig
Specificity This VCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 733~763 amino acids from the C-terminal region of human VCP.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Pig (Porcine),Rat (Rattus),Xenopus laevis,Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VCP (vcp Antibody Abstract)
Background VCP is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation.
Synonyms: Transitional endoplasmic reticulum ATPase, TER ATPase, 15S Mg(2+)-ATPase p97 subunit, Valosin-containing protein, VCP
Molecular Weight 89322 DA
Gene ID 7415
UniProt P55072
Research Area Neurology
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Valosin Containing Protein (vcp) (AA 726-755), (C-Term) antibody (ABIN390907) Western blot analysis of VCP Antibody (C-term) (ABIN390907) in Jurkat, 293, MDA-MB231...
Immunohistochemistry (IHC) image for anti-Valosin Containing Protein (vcp) (AA 726-755), (C-Term) antibody (ABIN390907) Formalin-fixed and paraffin-embedded human brain tissue reacted with VCP Antibody (C-...
Flow Cytometry (FACS) image for anti-Valosin Containing Protein (vcp) (AA 726-755), (C-Term) antibody (ABIN390907) Flow cytometric analysis of MDA-231 cells using VCP Antibody (C-term)(bottom histogra...
Product cited in: Ayaki, Ito, Fukushima, Inoue, Kondo, Ikemoto, Asano, Shodai, Fujita, Fukui, Morino, Nakano, Kusaka, Yamashita, Ihara, Matsumoto, Kawamata, Urushitani, Kawakami, Takahashi: "Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant." in: Acta neuropathologica communications, Vol. 2, pp. 172, 2015 (PubMed).

Background publications Rush, Moritz, Lee, Guo, Goss, Spek, Zhang, Zha, Polakiewicz, Comb: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).