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Anti-Mullerian Hormone Receptor, Type II (AMHR2) (AA 374-402), (C-Term) antibody

Details for Product No. ABIN391175, Supplier: Login to see
Antigen
  • AMHR
  • MISR2
  • MISRII
  • MRII
  • Misiir
  • Misrii
  • Mrii
Epitope
AA 374-402, C-Term
29
15
4
3
2
2
2
1
1
1
1
1
1
Reactivity
Human
63
21
15
Host
Rabbit
56
4
2
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
49
28
11
7
6
4
3
2
Supplier
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Immunogen This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 AA from the C-terminal region of human AMHR2.
Clone RB15726
Isotype Ig
Specificity This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381~410 amino acids from the N-terminal region of human AMHR2.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name AMHR2 (AMHR2 Antibody Abstract)
Background The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth, anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
Synonyms: Anti-Muellerian hormone type II receptor [Precursor], AMH type II receptor, MIS type II receptor, MISRII, MRII, AMHR2, AMHR,
Molecular Weight 62750 DA
Gene ID 269
UniProt Q16671
Research Area Phospho-specific antibodies, Stem Cells, Cell Signaling, Protein Modifications, Cell Structure
Pathways
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Anti-Mullerian Hormone Receptor, Type II (AMHR2) (AA 374-402), (C-Term) antibody (ABIN391175) Western blot analysis of AMHR2 Antibody (C-term) (ABIN391175) in CEM cell line lysate...
Western Blotting (WB) image for anti-Anti-Mullerian Hormone Receptor, Type II (AMHR2) (AA 374-402), (C-Term) antibody (ABIN391175) Western blot analysis of AMHR2 (arrow) using AMHR2 Antibody (C-term) (ABIN391175). 29...
Flow Cytometry (FACS) image for anti-Anti-Mullerian Hormone Receptor, Type II (AMHR2) (AA 374-402), (C-Term) antibody (ABIN391175) Flow cytometric analysis of CEM cells using AMHR2 Antibody (C-term)(bottom histogram)...
Product cited in: Carrarelli, Rocha, Belmonte et al.: "Increased expression of antimüllerian hormone and its receptor in endometriosis." in: Fertility and sterility, Vol. 101, Issue 5, pp. 1353-8, 2014 (PubMed).

Background publications Visser, McLuskey, van Beers et al.: "Structure and chromosomal localization of the human anti-müllerian hormone type II receptor gene." in: Biochemical and biophysical research communications, Vol. 215, Issue 3, pp. 1029-36, 1995 (PubMed).