NUAK2 antibody (N-Term)

Catalog No. ABIN391234

This Rabbit Polyclonal antibody specifically detects NUAK2 in WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for NUAK2 antibody (N-Term) (ABIN391234)

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUAK2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB8576

Product Details anti-NUAK2 Antibody

Binding Specificity: AA 67-96, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NUAK2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-NUAK2 antibody (ABIN391234)

Yamamoto, Takashima, Shintani, Yamazaki, Seguchi, Nakano, Higo, Kato, Liao, Asano, Minamino, Matsumura, Takeda, Kitakaze: "Identification of a novel substrate for TNFalpha-induced kinase NUAK2." in: Biochemical and biophysical research communications, Vol. 365, Issue 3, pp. 541-7, (2008) (PubMed).

Target Details for NUAK2

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Alternative Name: NUAK2

Background: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.

Molecular Weight: 69612

Gene ID: 81788

NCBI Accession: NP_112214

UniProt: Q9H093