NUAK2 antibody (Internal Region)

Catalog No. ABIN6263760

The Rabbit Polyclonal anti-NUAK2 antibody is suitable to detect NUAK2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for NUAK2 antibody (Internal Region) (ABIN6263760)

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUAK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NUAK2 Antibody

Binding Specificity: Internal Region

Specificity: NUAK2 Antibody detects endogenous levels of total NUAK2.

Predicted Reactivity: Pig,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NUAK2, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for NUAK2

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Alternative Name: NUAK2

Background:

Description: Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1.

Gene: NUAK2

Molecular Weight: 70kDa

Gene ID: 81788

UniProt: Q9H093