NUAK2 antibody

Catalog No. ABIN7230166

The Rabbit Polyclonal anti-NUAK2 antibody (ABIN7230166) specifically detects NUAK2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NUAK2 antibody (ABIN7230166)

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUAK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NUAK2 Antibody

Purpose: Rabbit Anti-NUAK2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NUAK2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NUAK2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NUAK2

Target: NUAK2 (NUAK Family, SNF1-Like Kinase, 2 (NUAK2))

Alternative Name: NUAK2

Background: NUAK family SNF1-like kinase 2, Omphalocele kinase 2, SNF1/AMP kinase-related kinase, SNARKNUAK2 (NUAK Family Kinase 2) is a Protein Coding gene. Among its related pathways are Cytoskeletal Signaling and Glucose / Energy Metabolism. Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate Ser-464 of LATS1.

Molecular Weight: 69kD

Gene ID: 81788

UniProt: Q9H093