Pantothenate Kinase 3 (PANK3) (AA 150-181), (Center) antibody

Details for Product No. ABIN391240
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Antigen
Synonyms MGC84572, fb79e08, zgc:63556, wu:fb79e08
Epitope
AA 150-181, Center
(4), (3), (2), (1), (1), (1)
Reactivity
Human
(30), (14), (14), (12), (12), (12), (12)
Host
Rabbit
(24), (6)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(20), (11), (10), (9), (2), (2), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN391240
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This PANK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-181 AA from the Central region of human PANK3.
Clone RB5577
Isotype Ig
Specificity This PANK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158~188 amino acids from the Center region of human PANK3.
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PANK3
Background PANK3 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.
Synonyms: Pantothenate kinase 3, Pantothenic acid kinase 3, hPanK3,
Molecular Weight 41094 DA
Gene ID 79646
UniProt Q9H999
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Pantothenate Kinase 3 (PANK3) (AA 150-181), (Center) antibody Western blot analysis of anti-PANK3 (ABIN391240) in HepG2 cell line lysate (35 µg/lane).PANK3(arrow) was detected using the purified polyclonal antibody (1:50 dilution).
anti-Pantothenate Kinase 3 (PANK3) (AA 150-181), (Center) antibody (2) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma
Background publications Zhou, Westaway, Levinson et al.: "A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome." in: Nature genetics, Vol. 28, Issue 4, pp. 345-9, 2001 (PubMed).

Hosts (24), (6)
Reactivities (30), (14), (14), (12), (12), (12), (12)
Applications (20), (11), (10), (9), (2), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (2), (1), (1), (1)
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