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Pantothenate Kinase 3 (PANK3) (AA 150-181), (Center) antibody

Details for Product No. ABIN391240, Supplier: Login to see
Antigen
  • MGC84572
  • fb79e08
  • zgc:63556
  • wu:fb79e08
Epitope
AA 150-181, Center
19
9
8
4
3
2
1
1
1
1
1
1
Reactivity
Human
65
16
16
Host
Rabbit
56
9
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
51
34
29
11
8
3
2
1
1
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Immunogen This PANK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-181 AA from the Central region of human PANK3.
Clone RB5577
Isotype Ig
Specificity This PANK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158~188 amino acids from the Center region of human PANK3.
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PANK3 (PANK3 Antibody Abstract)
Background PANK3 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver.
Synonyms: Pantothenate kinase 3, Pantothenic acid kinase 3, hPanK3,
Molecular Weight 41094 DA
Gene ID 79646
UniProt Q9H999
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Pantothenate Kinase 3 (PANK3) (AA 150-181), (Center) antibody (ABIN391240) Western blot analysis of anti-PANK3 (ABIN391240) in HepG2 cell line lysate (35 µg/lan...
Immunohistochemistry (IHC) image for anti-Pantothenate Kinase 3 (PANK3) (AA 150-181), (Center) antibody (ABIN391240) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Background publications Zhou, Westaway, Levinson et al.: "A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome." in: Nature genetics, Vol. 28, Issue 4, pp. 345-9, 2001 (PubMed).