Ornithine Decarboxylase Antizyme 1 (OAZ1) (N-Term) antibody

Antigen: Ornithine Decarboxylase Antizyme 1 (OAZ1)

Synonyms: AZI, OAZ, MGC138338, OAZI, OAZIN, ODC1L, MGC691, MGC3832

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN391689

Additional Information

Alternative name: OAZ1

Gene ID: 4946

UniProt: P54368

Immunogen: This OAZ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9~39 amino acids from the N-terminal region of human OAZ1.

Isotype: Ig

Description: Other names: Ornithine decarboxylase antizyme, ODC-Az , OAZ

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This OAZ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9~39 amino acids from the N-terminal region of human OAZ1.

Molecular Weight: 25406 DA

Comments:

Background: OAZ1 catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. This protein play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein expression is auto-regulated by polyamine-enhanced translational frameshifting.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100 Immunohistochemistry ~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cancer, Metabolism, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of OAZ1 Antibody (N-term) (ABIN391689) in mouse heart tissue lysates (35ug/lane). OAZ1 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded mouse heart tissue reacted with OAZ1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated.

Publications

Product: Grimwood, Gordon, Olsen et al.: "The DNA sequence and biology of human chromosome 19." in: Nature, Vol. 428, Issue 6982, pp. 529-35, 2004 (PubMed).