This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This IGFALS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the Central region of human IGFALS.
ALS antibody, Albs antibody, mKIAA4111 antibody, Als antibody, insulin like growth factor binding protein acid labile subunit antibody, insulin like growth factor binding protein acid labile subunit L homeolog antibody, insulin-like growth factor binding protein, acid labile subunit antibody, IGFALS antibody, igfals.L antibody, Igfals antibody
Background
IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this protein are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.