AXL antibody (C-Term)

Catalog No. ABIN391877

There is 1 publication for this product available. The Rabbit Polyclonal anti-AXL antibody is suitable to detect AXL in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for AXL antibody (C-Term) (ABIN391877)

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1483

Product Details anti-AXL Antibody

Binding Specificity: AA 863-894, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This AXL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 863-894 amino acids from the C-terminal region of human AXL.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Expiry Date: 6 months

References for anti-AXL antibody (ABIN391877)

Hu, Liu, Liu, Zheng, Liu, Luo, Gao, Zhao, Zou: "Role of axl in preeclamptic EPCs functions." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 36, Issue 3, pp. 395-401, (2017) (PubMed).

Target Details for AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Alternative Name: AXL

Background: AXL, a member of the AXL/UFO subfamily of Tyr protein kinases, may function as a signal transducer between specific cell types of mesodermal origin. This Type I membrane protein has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia. The protein contains 2 putative fibronectin type III domains and 2 putative immunoglobulin-like C2-type domains.

Molecular Weight: 98337

Gene ID: 558

NCBI Accession: NP_001690, NP_068713

UniProt: P30530

Pathways: RTK Signaling, Cellular Response to Molecule of Bacterial Origin