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Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibody

Details for Product No. ABIN391992, Supplier: Log in to see
Antigen
  • zgc:91970
  • sestrin-1
  • SESN1
  • XPA26
  • pa26
  • sest1
  • PA26
  • SEST1
  • 1110002G11Rik
  • AU044290
  • Pa26
  • Sest1
  • sesn1-A
Epitope
AA 312-341, C-Term
7
5
5
4
3
3
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
52
37
27
Host
Rabbit
52
3
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
41
18
11
7
4
2
1
1
1
1
1
Supplier
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Immunogen This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 AA from the C-terminal region of human Sestrin-1.
Clone RB18601
Isotype Ig
Specificity This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319~349 amino acids from the C-terminal region of human Sestrin-1.
Predicted Reactivity Monkey,Xenopus laevis
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name Sestrin-1 (SESN1 Antibody Abstract)
Background Sestrin-1 is involved in the reduction of peroxiredoxins. This protein may also be regulator of cellular growth.
Synonyms: Sestrin-1, p53-regulated protein PA26, SEST1, PA26, SESN1
Molecular Weight 56557 DA
Gene ID 27244
UniProt Q9Y6P5
Research Area Cell Cycle, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibody (ABIN391992) Western blot analysis of Sestrin-1 antibody (C-term) (ABIN391992) in mouse heart tiss...
Western Blotting (WB) image for anti-Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibody (ABIN391992) Sestrin-1 Antibody (C-term) (ABIN391992) western blot analysis in NCI-H460,HL-60 cell...
Flow Cytometry (FACS) image for anti-Sestrin 1 (SESN1) (AA 312-341), (C-Term) antibody (ABIN391992) Sestrin-1 Antibody (C-term) (ABIN391992) flow cytometric analysis of NCI-H460 cells (...
Background publications Budanov, Sablina, Feinstein et al.: "Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD." in: Science (New York, N.Y.), Vol. 304, Issue 5670, pp. 596-600, 2004 (PubMed).

Peeters, Debeer, Bairoch et al.: "PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse." in: Human genetics, Vol. 112, Issue 5-6, pp. 573-80, 2003 (PubMed).

Velasco-Miguel, Buckbinder, Jean et al.: "PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes." in: Oncogene, Vol. 18, Issue 1, pp. 127-37, 1999 (PubMed).