Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This LTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1493-1525 amino acids from the C-terminal region of human LTBP1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Saraon, Musrap, Cretu, Karagiannis, Batruch, Smith, Drabovich, Trudel, van der Kwast, Morrissey, Jarvi, Diamandis: "Proteomic profiling of androgen-independent prostate cancer cell lines reveals a role for protein S during the development of high grade and castration-resistant prostate cancer." in: The Journal of biological chemistry, Vol. 287, Issue 41, pp. 34019-31, (2012) (PubMed).
Target
LTBP1
(Latent Transforming Growth Factor beta Binding Protein 1 (LTBP1))
LTBP1 may be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. This protein may play critical roles in controlling and directing the activity of TGFB1, and it may have a structural role in the extra cellular matrix (ECM).