WW Domain Binding Protein 2 (WBP2) (C-Term), (AA 186-212) antibody

Details for Product No. ABIN392214
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Antigen
Epitope
C-Term, AA 186-212
(5), (3), (2)
Reactivity
Human
(22), (14), (14)
Host
Rabbit
(19), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(13), (10), (5), (3), (2), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN392214
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Immunogen This WBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-212 AA from the C-terminal region of human WBP2.
Clone RB15556
Isotype Ig
Specificity This WBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192~221 amino acids from the C-terminal region of human WBP2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name WBP2
Background The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. WBP2 is a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined.
Synonyms: WW domain-binding protein 2, WBP-2
Molecular Weight 28087 DA
Gene ID 23558
UniProt Q969T9
Research Area Cell Signaling, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-WW Domain Binding Protein 2 (WBP2) (C-Term), (AA 186-212) antibody Western blot analysis of anti-BP2 Antibody (C-term) (ABIN392213) in A2058 cell line lysates (35 µg/lane). BP2(arrow) was detected using the purified polyclonal antibody.
anti-WW Domain Binding Protein 2 (WBP2) (C-Term), (AA 186-212) antibody (2) Formalin-fixed and paraffin-embedded human brain tissue reacted with WBP2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
anti-WW Domain Binding Protein 2 (WBP2) (C-Term), (AA 186-212) antibody (3) Flow cytometric analysis of HepG2 cells using WBP2 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Dhananjayan, Ramamoorthy, Khan et al.: "WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors." in: Molecular endocrinology (Baltimore, Md.), Vol. 20, Issue 10, pp. 2343-54, 2006 (PubMed).

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