Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (C-Term), (AA 342-371) antibody

Details for Product No. ABIN392666
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Antigen
Synonyms SDPII, AI197433, SdpII, sdpii, zgc:77519, pacsin1, x-PACSIN2, PACSIN2, DKFZp459J1025
Epitope
C-Term, AA 342-371
(3), (3), (3), (1), (1)
Reactivity
Human, Mouse (Murine)
(22), (8), (4), (3), (3), (2), (2), (1), (1), (1)
Host
Rabbit
(19), (4)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(22), (10), (7), (3), (3), (1), (1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN392666
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This PACSIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 AA from the C-terminal region of human PACSIN2.
Clone RB3584
Isotype Ig
Specificity This PACSIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349~379 amino acids from the C-terminal region of human PACSIN2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PACSIN2
Background PACSIN may play a role in vesicle formation and transport. This protein homo- and hetero-aggregates with other PACSINs. It also binds dynamin 1, synaptojanin, synapsin 1 and the neural Wiskott-Aldrich syndrome protein (N-WASP). The protein exhibits a cvesicle-like cytoplasmic distribution and is ubiquitously expressed. PACSIN is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). The protein contains 1 FCH domain and 1 SH3 domain.
Synonyms: Protein kinase C and casein kinase substrate in neurons protein 2
Molecular Weight 55738 Da
Gene ID 11252
UniProt Q9UNF0
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes IF = 1:100, WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (C-Term), (AA 342-371) antibody The anti-PACSIN2 Pab (ABIN392666) is used in Western blot to detect PACSIN2 in T-47D cell lysate (Lane 1) and mouse brain tissue lysate (Lane 2).
anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) (C-Term), (AA 342-371) antibody (2) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma
Background publications Dunham, Shimizu, Roe et al.: "The DNA sequence of human chromosome 22...." in: Nature, Vol. 402, Issue 6761, pp. 489-95, 1999 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Hosts (19), (4)
Reactivities (22), (8), (4), (3), (3), (2), (2), (1), (1), (1)
Applications (22), (10), (7), (3), (3), (1), (1), (1), (1)
Epitopes (3), (3), (3), (1), (1)
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