tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide (YWHAZ) (AA 211-239), (Thr232) antibody

Details for Product No. ABIN392783
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Antigen
Synonyms
14-3-3z, 14-3-3zeta, ywhaz, ywhazb, 14-3-3-zeta, KCIP-1, YWHAD, 1110013I11Rik, AI596267, AL022924, AU020854, fb14h09, wu:fb05g08, wu:fb14h09, ywhai, zgc:55807, 14-3-3, 14-3-3 zeta, 14-3-3ZETA, 14-3-3l ... show more
14-3-3z, 14-3-3zeta, ywhaz, ywhazb, 14-3-3-zeta, KCIP-1, YWHAD, 1110013I11Rik, AI596267, AL022924, AU020854, fb14h09, wu:fb05g08, wu:fb14h09, ywhai, zgc:55807, 14-3-3, 14-3-3 zeta, 14-3-3ZETA, 14-3-3leo, 2G1, 4-3-3 zeta, 5.11, 549, BEST:GH05075, CG17870, D14-3-3, D14-3-3zeta, Dmel\\CG17870, K, LEO, Leo, PAR-5, PAR5, Par-5, d14-3-3zeta, l(2)07103, l(2)46CFe, l(2)46Ee, leo, par-5, ywhaza, kcip-1, ywhaq, Ywhaz, ACYPI003154, 1433z show less
Epitope
AA 211-239, Thr232
(37), (11), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(127), (80), (75), (16), (15), (15), (4), (2), (1), (1), (1), (1)
Host
Rabbit
(124), (9)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(118), (52), (46), (44), (37), (12), (10), (10), (3), (1), (1)
Pubmed 2 references available
Catalog no. ABIN392783
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
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Immunogen This YWHAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-239 AA from human YWHAZ.
Clone RB7161
Isotype Ig
Specificity This 14-3-3 protein zeta/delta antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding T232 of human 14-3-3.
Predicted Reactivity Cow (Bovine),Chicken,Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name 14-3-3 protein zeta/delta
Background 14-3-3 protein zeta/delta belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs.
Synonyms: 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ
Molecular Weight 27745 DA
Gene ID 7534
UniProt P63104
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide (YWHAZ) (AA 211-239), (Thr232) antibody Western blot analysis of anti-14-3-3 protein zeta/delta Anbtibody (T232)(ABIN392783) in A375 cell line lysates (35 µg/lane). 14-3-3 (arrow) was detected using the purified polyclonal antibody (1:60dilution).
anti-tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide (YWHAZ) (AA 211-239), (Thr232) antibody (2) Formalin-fixed and paraffin-embedded human testis tissue reacted with PLD1 antibody (N-term) (ABIN392783), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Li, Zhao, Du et al.: "Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 162-7, 2008 (PubMed).

Li, Mofunanya, Harris et al.: "Chibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activity." in: The Journal of cell biology, Vol. 181, Issue 7, pp. 1141-54, 2008 (PubMed).

Hosts (124), (9)
Reactivities (127), (80), (75), (16), (15), (15), (4), (2), (1), (1), (1), (1)
Applications (118), (52), (46), (44), (37), (12), (10), (10), (3), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (37), (11), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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