You are viewing an incomplete version of our website. Please click to reload the website as full version.

Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 234-265), (N-Term) antibody

Details for Product No. ABIN392828, Supplier: Login to see
Antigen
  • PTPRR
  • PTPRQ
  • ec-ptp
  • pcptp1
  • ptp-sl
  • ptpbr7
  • EC-PTP
  • PCPTP1
  • PTP-SL
  • PTPBR7
  • Gmcp1
  • RPTPRR
  • mPTP213
  • Pcptp1
Epitope
AA 234-265, N-Term
25
5
5
4
2
2
1
1
1
1
1
Reactivity
Human
85
27
24
3
2
2
2
1
Host
Rabbit
80
7
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
6
6
6
3
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
57
36
23
14
11
5
3
2
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-265 AA from the N-terminal region of human PCPTP1.
Clone RB0621
Isotype Ig
Specificity This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242~272 amino acids from the N-terminal region of human PCPTP1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PCPTP1 (PTPRR Antibody Abstract)
Background PCPTP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene for this protein predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of the gene for this protein was reported to be regulated by the nerve growth factor, which suggested a function in neuronal growth and differentiation.
Molecular Weight 73862 DA
Gene ID 5801
UniProt Q15256
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cancer, Cell Cycle, Neurology
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 234-265), (N-Term) antibody (ABIN392828) The anti-PCPTP1 Pab (ABIN392828) is used in Western blot to detect PCPTP1 in placenta...
Immunohistochemistry (IHC) image for anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (AA 234-265), (N-Term) antibody (ABIN392828) Formalin-fixed and paraffin-embedded human brain tissue reacted with hPCPTP1-Y249, wh...
Background publications Blanco-Aparicio, Torres, Pulido: "A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase." in: The Journal of cell biology, Vol. 147, Issue 6, pp. 1129-36, 2000 (PubMed).

Ogata, Sawada, Fujino et al.: "cDNA cloning and characterization of a novel receptor-type protein tyrosine phosphatase expressed predominantly in the brain." in: The Journal of biological chemistry, Vol. 270, Issue 5, pp. 2337-43, 1995 (PubMed).