ENPP3 antibody

Catalog No. ABIN400884

Product Details anti-ENPP3 Antibody

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ENPP3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificity: This Monoclonal antibody NP4D6 reacts with CD203c, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: E-NPP 3, PDNP3, Phosphodiesterase I beta, PD-I beta, Ectonucleotide pyrophosphatase /phosphodiesterase family member 3, Phosphodiesterase I/nucleotide pyrophosphatase 3

Purification: Affinity Chromatography on Protein A

Immunogen: HEK-293 cells transfected with human CD203c

Clone: NP4D6

Isotype: IgG1

Application Details

Application Notes: Flow cytometry. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C. Avoid repeated freezing andthawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for ENPP3

Target: ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))

Alternative Name: CD203c / ENPP3 (ENPP3 Products)

Synonyms: B10 antibody, CD203c antibody, NPP3 antibody, PD-IBETA antibody, PDNP3 antibody, Npp3 antibody, RB13-6 antibody, AI876438 antibody, ENPP3 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 3 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 3 L homeolog antibody, ENPP3 antibody, Enpp3 antibody, enpp3 antibody, enpp3.L antibody

Background: CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.Synonyms: E-NPP 3, Ectonucleotide pyrophosphatase / phosphodiesterase family member 3, PD-I beta, PDNP3, Phosphodiesterase I beta, Phosphodiesterase I/nucleotide pyrophosphatase 3

Gene ID: 5169

UniProt: O14638

Pathways: Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity