FANCE antibody (N-Term)

Catalog No. ABIN401269

Product Details anti-FANCE Antibody

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Binding Specificity: AA 1-13, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCE antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Sequence: M-A-T-P-D-A-G-L-P-G-A-E-G-C

Specificity: This antibody detects FANCE.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity chromatography

Immunogen: Synthetic peptide corresponding to amino acids 1-13 of Human FANCE

Isotype: IgG

Application Details

Application Notes: ELISA: 1: 4,000 to 1: 18,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for FANCE

Target: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Alternative Name: FANCE (FANCE Products)

Synonyms: FANCE antibody, fae antibody, face antibody, FACE antibody, FAE antibody, 2810451D06Rik antibody, AI415634 antibody, AW209126 antibody, RGD1561045 antibody, Fanconi anemia complementation group E antibody, Fanconi anemia, complementation group E antibody, FANCE antibody, fance antibody, Fance antibody

Background: FANCE promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage.Synonyms: FACE, Fanconi anemia group E protein

Gene ID: 2178

NCBI Accession: NP_068741

UniProt: Q9HB96

Pathways: DNA Damage Repair