Mre11 antibody (AA 578-590)

Catalog No. ABIN401304

Product Details anti-Mre11 Antibody

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Binding Specificity: AA 578-590

Reactivity: Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mre11 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Chromatin Immunoprecipitation (ChIP)

Specificity: This antibody is directed against Saccharomyces cerevisiae Mre11 protein.

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to amino acids 578-590 of Saccharomyces cerevisiae (baker's yeast) Mre11 protein

Isotype: IgG

Application Details

Application Notes: ELISA: 1/10000 - 1/50000. Western Blot: 1/200 - 1/2000. ChIP.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.19 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH containing 0.01 % (w/v) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Mre11

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Alternative Name: MRE11 (MRE11A Products)

Synonyms: wu:faa63d12 antibody, zgc:64018 antibody, Mre11 antibody, Mre11b antibody, ATLD antibody, HNGS1 antibody, MRE11 antibody, MRE11B antibody, MRE11 homolog A, double strand break repair nuclease antibody, MRE11 homolog, double strand break repair nuclease antibody, MRE11A homolog A, double strand break repair nuclease antibody, mre11a antibody, MRE11 antibody, Mre11a antibody

Background: Mre11 (also known as double-strand break repair protein MRE11) is a subunit of a complex with Rad50 and Xrs2 (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability. Mre11 possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity that appears to be required for RMX function. This nuclear protein is widely conserved and is also involved in meiotic double strand break processing.Synonyms: Double-strand break repair protein MRE11A, HNGS1, MRE11 homolog 1, MRE11 meiotic recombination 11 homolog A, MRE11A

Gene ID: 855264

NCBI Accession: NP_013951

UniProt: P32829

Pathways: DNA Damage Repair