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WNT1 antibody (Internal Region)

WNT1 Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Opossum WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN401405
  • Target See all WNT1 Antibodies
    WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
    Binding Specificity
    • 15
    • 11
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 63
    • 37
    • 11
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    Human, Mouse, Rat, Cow, Dog, Monkey, Opossum
    Host
    • 59
    • 4
    Rabbit
    Clonality
    • 59
    • 4
    Polyclonal
    Conjugate
    • 34
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WNT1 antibody is un-conjugated
    Application
    • 39
    • 27
    • 16
    • 14
    • 14
    • 12
    • 9
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts with Wnt1 protein.
    Cross-Reactivity (Details)
    Species reactivity (expected):Rat, Bovine, Canine, Macaque, Opossum.
    Species reactivity (tested):Human, Mouse.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    Synthetic peptide corresponding to an internal region of Human Wnt1 protein
    Isotype
    IgG
    Top Product
    Discover our top product WNT1 Primary Antibody
  • Application Notes
    ELISA: 1/25,000. Western Blot: 1/1,500 - 1/6,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.38 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
  • Target
    WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))
    Alternative Name
    WNT1 (WNT1 Products)
    Synonyms
    Xint-1 antibody, Xwnt1 antibody, int-1 antibody, int1 antibody, wnt-1 antibody, wnt1-a antibody, Int-1 antibody, Wnt-1 antibody, sw antibody, swaying antibody, BMND16 antibody, INT1 antibody, OI15 antibody, Int1 antibody, WNT-1 antibody, sb:eu647 antibody, zgc:194464 antibody, zgc:194478 antibody, WNT1 antibody, Wnt family member 1 antibody, Wnt family member 1 L homeolog antibody, wingless-type MMTV integration site family, member 1 antibody, WNT1 antibody, wnt1.L antibody, Wnt1 antibody, wnt1 antibody
    Background
    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt1 (Wingless-type MMTV integration site family member 1) is a member of the WNT gene family. It is highly conserved in evolution and the protein encoded by this gene is known to be 98 % identical to mouse Wnt1 protein at the amino acid level. Studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. Wnt1 is secreted as an extracellular matrix protein.Synonyms: INT-1, INT1, Proto-oncogene protein Wnt-1
    Gene ID
    7471
    NCBI Accession
    NP_005421
    UniProt
    P04628
    Pathways
    WNT Signaling, Dopaminergic Neurogenesis
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