F11R
Reactivity: Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Peptide ELISA: Detection Limit Dilution: 1/2000. Western blot: 0.3-2 μg/mL. Approx 38 kDa band observed in Human Peripheral BloodMononucleocyte lysates (calculated MW of 32.8 kDa according to NP_058642.1). Theobserved molecular weight corresponds to earlier findings with different antibodies fromother commercial sources. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Junctional Adhesion Molecule 1 (JAM1) seems to plays a role in epithelial tight junction formation. It appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. JAM1 plays a role in regulating monocyte transmigration involved in integrity of the epithelial barrier. JAM1 is also involved in platelet activation.Synonyms: F11R, JAM-A, JCAM, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM1, Platelet F11 receptor, Platelet adhesion molecule 1