Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN404814

High Mobility Group Nucleosome Binding Domain 1 (HMGN1) (Middle Region) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms HMG14, HMG-14, Hmg14, hmg14, hmgn1, hmgn1b
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Rabbit, Rat (Rattus), Mouse (Murine), Cow (Bovine), Dog (Canine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN404814
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-HMGN1 antibody: synthetic peptide directed towards the middle region of human HMGN1
Sequence PKKAAAKDKSSDKKVQTKGKRGAKGKQAEVANQETKEDLP AENGETKTEE
Predicted Reactivity Bovine : 100%, Human : 100%, Rabbit : 92%, Rat : 84%, Mouse : 76% Application WB, IHC
Characteristics This is a rabbit polyclonal antibody against HMGN1. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name HMGN1
Background Chromosomal protein HMG14 (HMGN1) and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.
Molecular Weight 11kDa
Gene ID 3150
NCBI Accession NP_004956, NM_004965
UniProt P05114
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-HMGN1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Zhu, Hansen: "HMGN1 modulates estrogen-mediated transcriptional activation through interactions with specific DNA-binding transcription factors." in: Molecular and cellular biology, Vol. 27, Issue 24, pp. 8859-73, 2007 (PubMed).

Alternatives for antigen "High Mobility Group Nucleosome Binding Domain 1 (HMGN1)", type "Antibodies"
Hosts (47)
Reactivities (46), (37), (37), (28), (27), (26), (26), (2), (1), (1)
Applications (23), (20), (17), (13), (12), (8), (2), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (17), (16), (5), (4), (3), (2), (1), (1), (1)
Beacon