HMGN1 antibody

Catalog No. ABIN7074222

The Rabbit Polyclonal anti-HMGN1 antibody is suitable to detect HMGN1 in samples from Mouse and Rat. It has been validated for WB, IHC and IF.

Quick Overview for HMGN1 antibody (ABIN7074222)

Target: HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HMGN1 Antibody

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse HMGN1

Application Details

Application Notes: WB (M,R) 1:500-1:1000, IHC/IF (M,R) 1:1000-1:4000/1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for HMGN1

Target: HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))

Alternative Name: HMGN1

Background: HMGN1 (high-mobility group nucleosome binding protein 1) is a member of the HMG super family of nonhistone chromatin-binding proteins, which which regulate chromatin structure and gene transcription. It binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. It may participate in the process which maintains transcribable genes in an unique chromatin conformation, and inhibit the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 expressed abundantly.

Molecular Weight: 17 kDa

Gene ID: 15312

NCBI Accession: NP_032277

UniProt: P18608

Pathways: Chromatin Binding