Homeobox C10 (HOXC10) (N-Term) antibody

Details for Product No. ABIN404815
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Antigen
Synonyms XHoxc10, MGC80182, HOXC10, HOXD10, HOX3I, AI506621, Hox-3.6
Epitope
N-Term
(16), (9), (9), (7), (7), (5), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Dog (Canine), Human
(42), (15), (3), (3)
Host
Rabbit
(38), (9), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (3), (3), (3)
Application
Western Blotting (WB)
(46), (28), (9), (8), (3), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN404815
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human HOXC10
Sequence GSDFNCGVMR GCGLAPSLSK RDEGSSPSLA LNTYPSYLSQ LDSWGDPKAA
Predicted Reactivity Human : 100 %, Dog : 80 %, Mouse : 80 %, Rabbit : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against HOXC10. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name HOXC10
Background HOXC10 belongs to the homeobox family. The homeobox family is a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.
Molecular Weight 38 kDa
Gene ID 3226
NCBI Accession NP_059105, NM_017409
UniProt Q9NYD6
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 342 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Zhai, Kuick, Nan et al.: "Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion." in: Cancer research, Vol. 67, Issue 21, pp. 10163-72, 2007 (PubMed).

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