HOXC10 antibody (C-Term)

Catalog No. ABIN1881429

Product Details anti-HOXC10 Antibody

Target: HOXC10 (Homeobox C10 (HOXC10))

Binding Specificity: AA 224-250, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXC10 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HOXC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-250 amino acids from the C-terminal region of human HOXC10.

Clone: RB42429

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HOXC10 antibody (ABIN1881429)

Hwang, Seok, Song, Jo, Lee: "HOXC10 as a potential marker for discriminating between amnion- and decidua-derived mesenchymal stem cells." in: Cloning and stem cells, Vol. 11, Issue 2, pp. 269-79, (2009) (PubMed).

Zhai, Kuick, Nan, Ota, Weiss, Trimble, Fearon, Cho: "Gene expression analysis of preinvasive and invasive cervical squamous cell carcinomas identifies HOXC10 as a key mediator of invasion." in: Cancer research, Vol. 67, Issue 21, pp. 10163-72, (2007) (PubMed).

Gabellini, Colaluca, Vodermaier, Biamonti, Giacca, Falaschi, Riva, Peverali: "Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression." in: The EMBO journal, Vol. 22, Issue 14, pp. 3715-24, (2003) (PubMed).

Kosaki, Kosaki, Suzuki, Yoshihashi, Takahashi, Sasaki, Tomita, McGinnis, Matsuo: "Complete mutation analysis panel of the 39 human HOX genes." in: Teratology, Vol. 65, Issue 2, pp. 50-62, (2002) (PubMed).

Sandrock, Egly: "A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH." in: The Journal of biological chemistry, Vol. 276, Issue 38, pp. 35328-33, (2001) (PubMed).

Target Details for HOXC10

Target: HOXC10 (Homeobox C10 (HOXC10))

Alternative Name: HOXC10 (HOXC10 Products)

Synonyms: HOX3I antibody, AI506621 antibody, Hox-3.6 antibody, XHoxc10 antibody, MGC80182 antibody, HOXC10 antibody, HOXD10 antibody, homeobox C10 antibody, homeobox C10 L homeolog antibody, homeo box C10 antibody, HOXC10 antibody, Hoxc10 antibody, hoxc10.L antibody

Background: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The protein level is controlled during cell differentiation and proliferation, which may indicate this protein has a role in origin activation.

Molecular Weight: 38073

NCBI Accession: NP_059105

UniProt: Q9NYD6