Chymotrypsin C (Caldecrin) (CTRC) (N-Term) antibody

Details for Product No. ABIN404904
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Antigen
Synonyms CLCR, ELA4, 1810044E12Rik, bPTLP
Epitope
N-Term
(2), (2), (1)
Reactivity
Mouse (Murine), Dog (Canine), Human
(4), (4), (1), (1)
Host
Rabbit
(5), (4), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(10), (6), (4), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN404904
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human CTRC
Sequence LGITVLAALL ACASSCGVPS FPPNLSARVV GGEDARPHSW PWQISLQYLK
Predicted Reactivity Human : 100 %, Dog : 80 %, Mouse : 80 %, Bovine : 70 %, Rat : 70 %
Characteristics This is a rabbit polyclonal antibody against CTRC. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CTRC
Background CTRC is a member of the peptidase S1 family. The protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Molecular Weight 27 kDa
Gene ID 11330
NCBI Accession NM_007272, NP_009203
UniProt Q99895
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 268 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Masson, Chen, Scotet et al.: "Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis." in: Human genetics, Vol. 123, Issue 1, pp. 83-91, 2008 (PubMed).

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