Potassium Channel, Subfamily V, Member 1 (KCNV1) (N-Term) antibody

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Antigen
Synonyms HNKA, KCNB3, KV2.3, KV8.1, 2700023A03Rik, vibe, Kv8.1
Epitope
N-Term
(20), (15), (13), (2), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(38), (18), (15)
Host
Rabbit
(38)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(22), (17), (15), (14), (11), (5)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human KCNV1
Blocking Peptide Blocking peptide for this product available: Potassium Channel, Subfamily V, Member 1 (KCNV1) (N-Term) peptide (ABIN978846)
Sequence ALGDCFTVNV GGSRFVLSQQ ALSCFPHTRL GKLAVVVASY RRPGALAAVP
Predicted Reactivity Human : 100 %, Mouse : 90 %, Rabbit : 90 %, Rat : 90 %, Bovine : 80 %, Dog : 80 %, Horse : 80 %
Characteristics This is a rabbit polyclonal antibody against KCNV1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name KCNV1 (KCNV1 Antibody Abstract)
Background Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNV1 is a member of the potassium voltage-gated channel subfamily V. This protein is essentially present in the brain, and its role might be to inhibit the function of a particular class of outward rectifier potassium channel types.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This protein is essentially present in the brain, and its role might be to inhibit the function of a particular class of outward rectifier potassium channel types.
Molecular Weight 56 kDa
Gene ID 27012
NCBI Accession NP_055194, NM_014379
UniProt Q6PIU1
Research Area Neurology
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 500 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Potassium Channel, Subfamily V, Member 1 (KCNV1) (N-Term) antibody (ABIN405111) WB Suggested Anti-KCNV1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Gutman, Chandy, Grissmer et al.: "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels." in: Pharmacological reviews, Vol. 57, Issue 4, pp. 473-508, 2005 (PubMed).

Catalog No. ABIN405111
$289.00
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