HIF1AN antibody (Middle Region)

Catalog No. ABIN405217

This Rabbit Polyclonal antibody specifically detects HIF1AN in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Dog, Horse, Cow, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for HIF1AN antibody (Middle Region) (ABIN405217)

Target: HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Horse, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIF1AN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIF1AN Antibody

Binding Specificity: Middle Region

Sequence: GGITITVNFW YKGAPTPKRI EYPLKAHQKV AIMRNIEKML GEALGNPQEV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HIF1AN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIF1AN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIF1AN

Target: HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))

Alternative Name: HIF1AN

Background: HIF1AN is a co-repressor that interacts with hypoxia-inducible factor 1 (HIF-1) alpha and the von Hippel-Lindau tumor suppressor protein to mediate repression of HIF-1 transcriptional activity.
Alias Symbols: DKFZp762F1811, FIH1, FLJ20615, FLJ22027
Protein Interaction Partner: HIF1A, ASB8, ASB7, ASB6, ASB5, ASB16, UACA, FEM1B, NFKB1, ASB9, UBC, UBD, HIF1AN, UBE3A, ELAVL1, OTUD7B, FBF1, ASB13, HDAC3, INVS, HDAC2, HDAC1, VHL, ASB4, SIAH1,
Protein Size: 349

Molecular Weight: 40 kDa

Gene ID: 55662

NCBI Accession: NM_017902, NP_060372

UniProt: Q9NWT6

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development