Solute Carrier Family 22 (Organic Anion Transporter), Member 8 (SLC22A8) (Middle Region) antibody

Details for Product No. ABIN405412
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Antigen
Synonyms OAT3, OCT3, Oat3, Roct, EMT, EMTH, Oct3, Orct3, Slca22a3
Epitope
Middle Region
(4), (3), (1), (1), (1), (1)
Reactivity
Rabbit, Mouse (Murine), Cow (Bovine), Dog (Canine), Human
(36), (30), (24)
Host
Rabbit
(38), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(29), (18), (11), (10), (3), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN405412
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human SLC22A8
Sequence PETLNQPLPE TIEDLENWSL RAKKPKQEPE VEKASQRIPL QPHGPGLGSS
Predicted Reactivity Human : 100 %, Dog : 70 %
Characteristics This is a rabbit polyclonal antibody against SLC22A8. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SLC22A8
Background SLC22A8 is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. SLC22A8 is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney.The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney.
Molecular Weight 60 kDa
Gene ID 9376
NCBI Accession NM_004254, NP_004245
UniProt Q8TCC7
Research Area Signaling, Metabolism
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 542 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Windass, Lowes, Wang et al.: "The contribution of organic anion transporters OAT1 and OAT3 to the renal uptake of rosuvastatin." in: The Journal of pharmacology and experimental therapeutics, Vol. 322, Issue 3, pp. 1221-7, 2007 (PubMed).

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