Tripartite Motif Containing 55 (TRIM55) (N-Term) antibody

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Antigen
Synonyms TRIM55, MURF-2, RNF29, muRF2, D830041C10Rik, Murf2, Rnf29, trim55, wu:fb71c01, zgc:92123
Epitope
N-Term
(5), (4), (4), (4), (2), (2), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(21), (9), (8), (4), (3), (3), (2), (2), (1), (1), (1)
Host
Rabbit
(14), (6), (2)
Clonality
Polyclonal
Application
Western Blotting (WB)
(20), (6), (1), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human TRIM55
Blocking Peptide Blocking peptide for this product available: Tripartite Motif Containing 55 (TRIM55) (N-Term) peptide (ABIN985562)
Sequence SGGRFRCPSC RHEVVLDRHG VYGLQRNLLV ENIIDIYKQE STRPEKKSDQ
Specificity 100 % homologous to all four isoforms of TRIM55.
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against TRIM55. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TRIM55 (TRIM55 Antibody Abstract)
Background TRIM55 contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres.The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described.
Molecular Weight 60 kDa
Gene ID 84675
NCBI Accession NP_908973, NM_184085
UniProt Q9BYV6
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 548 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Tripartite Motif Containing 55 (TRIM55) (N-Term) antibody (ABIN405554) anti-Tripartite Motif Containing 55 (TRIM55) (N-Term) antibody
Background publications Lange, Xiang, Yakovenko et al.: "The kinase domain of titin controls muscle gene expression and protein turnover." in: Science (New York, N.Y.), Vol. 308, Issue 5728, pp. 1599-603, 2005 (PubMed).

Catalog No. ABIN405554
$289.00
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