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Dynein, Axonemal, Light Intermediate Chain 1 (DNALI1) (N-Term) antibody

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Antigen
Synonyms zgc:171493, zgc:171595, P28, dJ423B22.5, hp28, 1700023A09Rik, AW049135
Epitope
N-Term
(20), (16), (8), (5), (2), (2), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(47), (10), (10), (1), (1), (1), (1)
Host
Rabbit
(40), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(43), (23), (6), (5), (1), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human DNALI1
Blocking Peptide Blocking peptide for this product available: ABIN975923
Sequence MVTANKAHTG QGSCWVATLA SAMIPPADSL LKYDTPVLVS RNTEKRSPKA
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Mouse : 100 %, Rabbit : 100 %
Characteristics This is a rabbit polyclonal antibody against DNALI1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name DNALI1 (DNALI1 Antibody Abstract)
Background DNALI1 is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Molecular Weight 31 kDa
Gene ID 7802
NCBI Accession NP_003453, NM_003462
UniProt O14645
Research Area Signaling, Cytoskeleton
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 280 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Dynein, Axonemal, Light Intermediate Chain 1 (DNALI1) (N-Term) antibody (ABIN406364) WB Suggested Anti-DNALI1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Combs, Kim, Tan et al.: "Recruitment of dynein to the Jurkat immunological synapse." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 40, pp. 14883-8, 2006 (PubMed).

Catalog No. ABIN406364
$289.00
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