TUSC1 antibody (Middle Region)

Catalog No. ABIN406396

This Rabbit Polyclonal antibody specifically detects TUSC1 in WB. It exhibits reactivity toward Human, Mouse, Cow and Pig.

Quick Overview for TUSC1 antibody (Middle Region) (ABIN406396)

Target: TUSC1 (Tumor Suppressor Candidate 1 (TUSC1))

Reactivity: Human, Mouse, Cow, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUSC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TUSC1 Antibody

Binding Specificity: Middle Region

Purpose: TUSC1 Antibody - middle region

Sequence: DSGREDEPGS PRALRARLEK LEAMYRRALL QLHLEQRGPR PSGDKEEQPL

Predicted Reactivity: Cow: 92%, Human: 100%, Mouse: 92%, Pig: 92%

Characteristics: This is a rabbit polyclonal antibody against TUSC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TUSC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54383-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TUSC1

Target: TUSC1 (Tumor Suppressor Candidate 1 (TUSC1))

Alternative Name: TUSC1

Background:

Background Information: Tusc1 gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.

Gene Name: Tumor suppressor candidate 1

Alternative Symbols: TSG9, TSG-9, CCDC89B

Protein Name: Tumor suppressor candidate gene 1 protein

Molecular Weight: 23kDa

Gene ID: 286319

NCBI Accession: NP_001004125

UniProt: Q2TAM9