Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody

Details for Product No. ABIN452704, Supplier: Log in to see
Antigen
  • acaDM
  • ACAD1
  • MCAD
  • MCADH
  • AU018656
  • acyl-CoA dehydrogenase
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain
  • acyl-Coenzyme A dehydrogenase, medium chain
  • acd
  • ACADM
  • acadm
  • Acadm
Alternatives
anti-Human Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 196-225
20
10
8
7
5
4
4
2
1
1
1
1
Reactivity
Human, Mouse (Murine)
104
48
40
7
5
4
4
2
2
1
1
1
Host
Rabbit
77
21
9
Clonality
Polyclonal
Conjugate
Un-conjugated
4
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
86
33
33
26
15
13
10
5
3
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen KLH conjugated synthetic peptide between 196~225 amino acids from the Center region of Human ACADM.
Isotype Ig
Specificity This antibody detects ACADM at Center.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name ACADM (ACADM Antibody Abstract)
Background ACADM protein is a medium chain specific (C4 to C12 straight chain) acyl Coenzyme A dehydrogenase. The enzyme catalyzes the initial step of the mitochondrial fatty acid beta oxidation pathway. ACADM expression is induced during periods of fasting, when reliance on fatty acids for energy is increased. Clinical phenotypes are associated with ACADM hereditary deficiency.Synonyms: MCAD, Medium-chain specific acyl-CoA dehydrogenase mitochondrial
Molecular Weight 46588 Da
Gene ID 34
NCBI Accession NP_000007
UniProt P11310
Research Area Cancer, Metabolism
Pathways Regulation of Lipid Metabolism by PPARalpha, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Monocarboxylic Acid Catabolic Process
Application Notes Western blot: 1: 50 - 1: 100. ELISA: 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (ABIN452704) anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody
 image for anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (ABIN452704) anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (Image 2)
 image for anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (ABIN452704) anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (Image 3)
 image for anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (ABIN452704) anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) (AA 196-225) antibody (Image 4)
Background publications Ferreira, Orlandi, Oliveira, Malta, Caxito, Gomes, Valadares, Godard: "A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil." in: Genetics and molecular research : GMR, Vol. 8, Issue 2, pp. 487-93, 2009 (PubMed).

Did you look for something else?