O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT) (C-Term) antibody

Antigen: O-Linked N-Acetylglucosamine (GlcNAc) Transferase (UDP-N-Acetylglucosamine:polypeptide-N-Acetylglucosaminyl Transferase) (OGT)

Synonyms: HRNT1, FLJ23071, MGC22921, O-GLCNAC, MGC80426, MGC69550

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Enzyme Immunoassay (EIA), Western Blotting (WB)

Catalog no.: ABIN453239

Additional Information

Characteristics: Synonyms: O-GlcNAc transferase subunit p110, UDP-N-acetylglucosamine--peptideN-acetylglucosaminyltransferase 110 kDa subunit, O-linked N-acetylglucosaminetransferase 110 kDa subunit

Alternative name: OGT

Gene ID: 8473

Swiss-Prot: O15294

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human OGT

Cross-Reactivity: Human, Mouse (Murine)

Description: O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of asingle N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Sinceboth phosphorylation and glycosylation compete for similar serine or threonine residues,the two processes may compete for sites, or they may alter the substrate specificity ofnearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptiderepeats and a putative bipartite nuclear localization signal.

Specificity: This antibody reacts to OGT. Species: Human, Mouse. Others not tested.

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 0.25 mg/ml

Buffer: PBS with 0.09% (W/V) sodium azide

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only