ESRRA antibody (Middle Region)

Catalog No. ABIN453642

Product Details anti-ESRRA Antibody

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRA antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to ESRRA.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human ESRRA

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Alternative Name: Estrogen-Related Receptor alpha (ESRRA Products)

Synonyms: err1 antibody, erra antibody, esrral antibody, erralpha antibody, nr3b1 antibody, MGC80854 antibody, ESRRA antibody, esrl1 antibody, LOC100125507 antibody, ERRalpha antibody, Err1 antibody, Estrra antibody, Nr3b1 antibody, Errra antibody, ERR1 antibody, ERRa antibody, ESRL1 antibody, NR3B1 antibody, ESTRRA antibody, estrogen-related receptor alpha antibody, estrogen related receptor alpha L homeolog antibody, estrogen related receptor alpha antibody, catsper channel auxiliary subunit zeta antibody, estrogen related receptor, alpha antibody, esrra antibody, esrra.L antibody, ESRRA antibody, LOC100125507 antibody, CATSPERZ antibody, Esrra antibody

Background: ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.Synonyms: ERR1, ESRL1, ESRRA, Estrogen receptor-like 1, NR3B1, Nuclear receptor subfamily 3 group B member 1, Steroid hormone receptor ERR1

Gene ID: 2101

NCBI Accession: NP_004442

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha