PDGFRB antibody (pTyr740)

Catalog No. ABIN482233

This Rabbit Polyclonal antibody specifically detects PDGFRB in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDGFRB antibody (pTyr740) (ABIN482233)

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PDGFRB Antibody

Binding Specificity: AA 711-760, pTyr740

Specificity:

PDGFR beta (Phospho-Tyr740) Antibody detects endogenous levels of PDGFR beta only when phosphorylated at Tyr740.

PhosphorylationH:Y740 M:Y739 R:Y739

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PDGFR beta around the phosphorylation site of Tyr740.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

Comment:

Unigene-Number: Hs.509067 (NCBI Gene Symbol: PDGFRB)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Alternative Name: PDGFR beta

Background:

Synonyms: CD140b, kinase PDGFR-beta, PDGF-R-beta, PDGFR, PDGFR-beta, PGFRB, platelet-derived growth factor receptor, beta polypeptide

NCBI Gene Symbol: PDGFRB

Molecular Weight: 123 kDa

Gene ID: 5159

OMIM: 131440

UniProt: P09619

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling