TRF1 antibody (pSer219)

Catalog No. ABIN482369

The Rabbit Polyclonal anti-TRF1 antibody is suitable to detect TRF1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for TRF1 antibody (pSer219) (ABIN482369)

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRF1 Antibody

Binding Specificity: AA 185-234, pSer219

Specificity:

Telomeric Repeat Binding Factor 1 (Phospho-Ser219) Antibody detects endogenous levels of Telomeric Repeat Binding Factor 1 only when phosphorylated at Ser219.

PhosphorylationH:S219 M:S206

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Telomeric Repeat Binding Factor 1 around the phosphorylation site of Ser219.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:5000

Comment:

Unigene-Number: Hs.442707 (NCBI Gene Symbol: TERF1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Alternative Name: Telomeric Repeat Binding Factor 1

Background:

Synonyms: NIMA-interacting protein 2, PIN2, TERF1, TRF, TTAGGG repeat binding factor 1, Telomeric protein Pin2/TRF1, Telomeric repeat binding factor 1

NCBI Gene Symbol: TERF1

Molecular Weight: 50 kDa

Gene ID: 7013

OMIM: 600951

UniProt: P54274

Pathways: Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity