IGF1R antibody (pTyr1161)

Catalog No. ABIN482482

This Rabbit Polyclonal antibody specifically detects IGF1R in WB, IHC, ELISA and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IGF1R antibody (pTyr1161) (ABIN482482)

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF1R antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-IGF1R Antibody

Binding Specificity: AA 1131-1180, pTyr1161

Specificity:

IGF1R (Phospho-Tyr1161) Antibody detects endogenous levels of IGF1R only when phosphorylated at Tyr1161.

PhosphorylationH:Y1161/Y1185 M:Y1163/Y1175 R:Y1162/Y1186

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1161.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.643120, Hs.653608, Hs.714012, Hs.465744 (NCBI Gene Symbol: IGF1R)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for IGF1R

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Alternative Name: IGF1R

Background:

Synonyms: CD221, IGF1R, Insulin-like growth factor I receptor precursor, kinase IGF1R

NCBI Gene Symbol: IGF1R

Molecular Weight: 154 kDa

Gene ID: 3480

OMIM: 147370

UniProt: P08069, P06213

Pathways: RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy