IGF1R antibody (pTyr1165)

Catalog No. ABIN482483

The Rabbit Polyclonal anti-IGF1R antibody is suitable to detect IGF1R in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for IGF1R antibody (pTyr1165) (ABIN482483)

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF1R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IGF1R Antibody

Binding Specificity: AA 1131-1180, pTyr1165

Specificity:

IGF1R (Phospho-Tyr1165/Tyr1166) Antibody detects endogenous levels of IGF1R only when phosphorylated at Tyr1165/Tyr1166.

PhosphorylationH:Y1165+Y1166/Y1189+Y1190 M:Y1167+Y1168/Y1179+Y1180 R:Y1166+Y1167/Y1190+Y1191

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1165/Tyr1166.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:20000

Comment:

Unigene-Number: Hs.643120, Hs.653608, Hs.714012 (NCBI Gene Symbol: IGF1R)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for IGF1R

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Alternative Name: IGF1R

Background:

Synonyms: CD221, IGF1R, Insulin-like growth factor I receptor precursor, kinase IGF1R

NCBI Gene Symbol: IGF1R

Molecular Weight: 154 kDa

Gene ID: 3480

OMIM: 147370

UniProt: P08069

Pathways: RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy