NFKBIA antibody (pTyr42)

Catalog No. ABIN482484

The Rabbit Polyclonal anti-NFKBIA antibody (ABIN482484) specifically detects NFKBIA in IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NFKBIA antibody (pTyr42) (ABIN482484)

Target: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFKBIA antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-NFKBIA Antibody

Binding Specificity: AA 9-58, pTyr42

Specificity:

IkappaB-alpha (Phospho-Tyr42) Antibody detects endogenous levels of IkappaB-alpha only when phosphorylated at Tyr42.

PhosphorylationH:Y42 M:Y42 R:Y42

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IkappaB-alpha around the phosphorylation site of Tyr42.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Comment:

Unigene-Number: Hs.81328 (NCBI Gene Symbol: NFKBIA)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for NFKBIA

Target: NFKBIA (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))

Alternative Name: IkappaB-alpha

Background:

Synonyms: I-kappa-B-alpha, IkappaBalpha, IKBA, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappaB inhibitor alpha, NFKBI, NFKBIA, RL/IF-1

NCBI Gene Symbol: NFKBIA

Molecular Weight: 35 kDa

Gene ID: 4792

OMIM: 164008

UniProt: P25963

Pathways: NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling