GTF2H4 antibody (N-Term)

Catalog No. ABIN486878

The Rabbit Polyclonal anti-GTF2H4 antibody has been validated for WB. It is suitable to detect GTF2H4 in samples from Human, Mouse, Rat, Guinea Pig, Dog, Cow, Goat, Rabbit and Horse.

Quick Overview for GTF2H4 antibody (N-Term) (ABIN486878)

Target: GTF2H4 (General Transcription Factor IIH, Polypeptide 4, 52kDa (GTF2H4))

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Cow, Goat, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2H4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GTF2H4 Antibody

Binding Specificity: N-Term

Sequence: ALWVKKEFSK AQEESTGLLS GLRIWHTQLL PGGLQGLILN PIFRQNLRIA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GTF2H4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2H4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 462 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF2H4

Target: GTF2H4 (General Transcription Factor IIH, Polypeptide 4, 52kDa (GTF2H4))

Alternative Name: GTF2H4

Background: GTF2H4 belongs to the TFB2 family. It is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
Alias Symbols: TFIIH, TFB2
Protein Interaction Partner: UBC, CDK7, RNF11, TP53, MNAT1, GTF2H3, GTF2H2, GTF2H1, ERCC3, CCNH, XBP1P1, MYC, GTF2E1, ERCC5, MED21, BTAF1, TBP, POLR2A, GTF2F1, GTF2B, BRCA1,
Protein Size: 462

Molecular Weight: 52 kDa

Gene ID: 2968

NCBI Accession: NM_001517, NP_001508

UniProt: Q92759

Pathways: DNA Damage Repair