Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN487066

T-Box 3 (TBX3) (Middle Region) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms D5Ertd189e, UMS, XHL, TBX3-ISO, xtbx3, ums, xhl, tbx3-iso, TBX3
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN487066
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-TBX3 antibody: synthetic peptide directed towards the middle region of human TBX3
Sequence VGTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTT SEEPCRDKGS
Predicted Reactivity Horse : 100%, Human : 100%, Pig : 100%, Rabbit : 100%, Bovine : 92%, Dog : 92%, Mouse : 92%, Rat : 92%, Guinea pig : 91%
Characteristics This is a rabbit polyclonal antibody against TBX3. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name TBX3
Background TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.
Molecular Weight 79kDa
Gene ID 6926
NCBI Accession NP_057653, NM_016569
UniProt O15119
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-TBX3 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Yarosh, Barrientos, Esmailpour et al.: "TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases." in: Cancer research, Vol. 68, Issue 3, pp. 693-9, 2008 (PubMed).

Alternatives for antigen "T-Box 3 (TBX3)", type "Antibodies"
Hosts (59), (10), (1)
Reactivities (66), (48), (44), (26), (25), (25), (1), (1)
Applications (48), (37), (19), (12), (7), (4), (4), (4), (1)
Conjugates (6), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (13), (7), (2), (2), (2), (2), (1), (1)
Beacon