PINX1 antibody (Internal Region)

Catalog No. ABIN487973

Product Details anti-PINX1 Antibody

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Binding Specificity: AA 225-237, Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PINX1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to PINX1.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-ESYLQPKAKRHTE, from the internal region of the protein sequence according to NP_060354.4.

Application Details

Application Notes: Peptide ELISA: 1/16000. Western blot: Approx 40 kDa band observed in lysates of cell lines A549, HepG2 and K562(calculated MW of 37.0 kDa according to NP_060354.4). Recommended concentration: 0.3 - 1.0 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for PINX1

Target: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Alternative Name: PINX1 (PINX1 Products)

Synonyms: PINX1 antibody, LPTL antibody, LPTS antibody, 2210403I16Rik antibody, 2610028A01Rik antibody, 67-11-3 antibody, AU024023 antibody, LPTS1 antibody, RGD1566025 antibody, PIN2/TERF1 interacting telomerase inhibitor 1 antibody, PIN2/TERF1 interacting, telomerase inhibitor 1 antibody, PINX1 antibody, Pinx1 antibody

Background: PINX1 (PIN2-interacting protein 1) is a ubiquitously expressed protein that localizes to nucleoli and telomere speckles. It contains a TID (telomerase inhibiting domain) domain which is capable of binding MCRS1, TERT and TERF1 and has been shown to be a potent telomerase inhibitor and putative tumor suppressor.Synonyms: LPTL, LPTS, Liver-related putative tumor suppressor, Pin2-interacting protein X1, Protein 67-11-3, TRF1-interacting protein 1

Gene ID: 54984

NCBI Accession: NP_060354

UniProt: Q96BK5