Flotillin 2 antibody (C-Term)

Catalog No. ABIN488109

Product Details anti-Flotillin 2 Antibody

Target: Flotillin 2 (FLOT2)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Flotillin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: Recognizes Flotillin-2/FLOT2.
Cellular Localization: Cell membrane, Peripheral membrane protein, Membrane, caveola, Peripheral membrane protein.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 365 and 378 of Flotillin-2

Application Details

Application Notes: Western blot: 1/500-1/3000Immunofluorescence: 1/100-1/200. Immunohistochemistry with Formalin-Fixed Paraffin-Embedded Sections : 1/100-1/250. Positive Controls: HeLaS3.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 1xPBS, 1 % BSA, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted at (in aliquots) at -20 °C.

Target Details for Flotillin 2

Target: Flotillin 2 (FLOT2)

Alternative Name: Flotillin-2 / FLOT2 (FLOT2 Products)

Synonyms: ECS-1 antibody, ECS1 antibody, ESA antibody, ESA1 antibody, M17S1 antibody, AI573412 antibody, Esa antibody, reggie-2 antibody, CG11547 antibody, CG14409 antibody, CG32593 antibody, DmFlo2 antibody, Dmel\\CG32593 antibody, FLO2 antibody, FLO[Dm]-2 antibody, Flo2 antibody, flo2 antibody, reggie-1 antibody, ecs-1 antibody, ecs1 antibody, esa antibody, esa1 antibody, flotillin-2 antibody, FLOT2 antibody, fb48a04 antibody, im:7143869 antibody, wu:fb48a04 antibody, zgc:55821 antibody, flotillin 2 antibody, Flotillin 2 antibody, flotillin 2 L homeolog antibody, flotillin 2a antibody, FLOT2 antibody, Flot2 antibody, Flo2 antibody, flot2.L antibody, flot2 antibody, flot2a antibody

Background: Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. Flotillin 2 may act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.Synonyms: ESA, ESA1, Epidermal surface antigen, M17S1, REG-1, Reg1, Reggie-1

Molecular Weight: 47 kDa

Gene ID: 2319

NCBI Accession: NP_004466

UniProt: Q14254