CD3 antibody (PE)
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- Target See all CD3 Antibodies
- CD3
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD3 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
- Purification
- Protein A purified
- Immunogen
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Purified human CD3 proteins isolated from thymus.
Type of Immunogen: Purified protein - Clone
- APA1-1
- Isotype
- IgG1
- Top Product
- Discover our top product CD3 Primary Antibody
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- Application Notes
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Approved: Flo
Usage: The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5 microgram/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 15 mM sodium azide, 0.2 % BSA, PBS
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze. Product is photosensitive and should be protected from light.
- Storage
- 4 °C
- Storage Comment
- Store at 4°C. Do not freeze. Protect from light.
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- Target
- CD3
- Alternative Name
- CD3 (CD3 Products)
- Synonyms
- CD3 antibody, AI504783 antibody, CD3epsilon antibody, T3e antibody, cd3-gamma antibody, cd3g antibody, cd3g-a antibody, cd3g/d antibody, cd3gd antibody, t3g antibody, CD3e molecule antibody, CD3d molecule antibody, CD3 antigen, epsilon polypeptide antibody, CD3g molecule S homeolog antibody, CD3E antibody, CD3D antibody, Cd3e antibody, cd3g.S antibody
- Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
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