NPC1 antibody (AA 1039-1052)

Catalog No. ABIN490718

Product Details anti-NPC1 Antibody

Target: NPC1 (Niemann-Pick Disease, Type C1 (NPC1))

Binding Specificity: AA 1039-1052

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This NPC1 antibody is un-conjugated

Application: ELISA

Specificity: Mouse NPC1.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Mouse (100%), Rat (93%), Hamster (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-TYHTILKTSADYTD from an internal region of mouse NPC1 (NP_032746.2). Percent identity with other species by BLAST analysis: Mouse (100%), Rat (93%), Hamster (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:16000)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Preliminary experiments gave an approx 36  kDa band in lysates of cell lines NIH3T3 and NSO after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 142  kDa according to NP_032746.2. The 36  kDa band was successfully blocked by incubation with the immunizing peptide.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for NPC1

Target: NPC1 (Niemann-Pick Disease, Type C1 (NPC1))

Alternative Name: NPC / NPC1 (NPC1 Products)

Synonyms: NPC antibody, 9130221N23Rik antibody, Gm243 antibody, Cdig2 antibody, im:7149020 antibody, wu:fb53a12 antibody, wu:fc29a12 antibody, A430089E03Rik antibody, C85354 antibody, D18Ertd139e antibody, D18Ertd723e antibody, lcsd antibody, nmf164 antibody, spm antibody, NPC intracellular cholesterol transporter 1 antibody, NPC1 like intracellular cholesterol transporter 1 antibody, Niemann-Pick disease, type C1 antibody, Niemann-Pick C1 protein antibody, NPC1 antibody, Npc1l1 antibody, Npc1 antibody, npc1 antibody, LOC579887 antibody

Background: Name/Gene ID: NPC1

Synonyms: NPC1, NPC, Niemann-Pick C1 protein, Niemann-Pick disease, type C1

Gene ID: 4864

NCBI Accession: NP_032746