Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody

Details for Product No. ABIN492380
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Antigen
Synonyms
CG8893, Dmel\\CG8893, GA3PDH, GADPH, GAP, GAPDH, GAPDH II, GAPDH2, Gapd, Gapdh, Gapdh-2, Gapdh13F, GAPD, g3pd, gapd, GB14798, GAPC-2, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE C-2, T6J4.17, T6J4_17, gl ... show more
CG8893, Dmel\\CG8893, GA3PDH, GADPH, GAP, GAPDH, GAPDH II, GAPDH2, Gapd, Gapdh, Gapdh-2, Gapdh13F, GAPD, g3pd, gapd, GB14798, GAPC-2, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE C-2, T6J4.17, T6J4_17, glyceraldehyde-3-phosphate dehydrogenase C2, BEST:GH12586, CG12055, Dmel\\CG12055, GAPDH I, GAPDH-1, GAPDH1, GAPDHI, Gapdh-1, Gapdh43E, gadph, gapdh, gapdh-1, gh12586, KNC-NDS6, G3PD, cb609, mg:bb02e05, wu:fb33a10, wu:ft80f05, G3PDH show less
Epitope
AA 1-335, N-Term
(83), (36), (14), (13), (10), (9), (8), (7), (7), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(400), (199), (168), (90), (42), (32), (29), (26), (18), (18), (17), (14), (12), (10), (9), (9), (8), (8), (7), (6), (6), (6), (4), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Mouse
(271), (192), (34), (18), (16)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(31), (28), (11), (6), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(467), (211), (134), (83), (75), (65), (31), (30), (28), (19), (15), (10), (6), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 0.1 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN492380
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Immunogen Recombinant human GAPDH (1-335aa) purified from E. coli
Clone AT8G4
Isotype IgG2b
Specificity The antibody recognizes GAPDH.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Characteristics Synonyms: GAPD, CDABP0047, Loading control, Glyceraldehyde-3-Phosphate Dehydrogenase
Purification Protein-G affinity chromatography
Alternative Name GAPDH
Background Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently appreciated. GAPDH is found in the particulate fractions, such as the nucleus, the mitochondria, and the small vesicular fractions. GAPDH gene expression is specifically increased during programmed neuronal cell death. When cells are exposed to various stressors, dynamic subcellular re-distribution of GAPDH occurs. GAPDH is also involved in various diseases, especially neurodegenerative disorders and cancers. As a membrane protein, GAPDH functions in endocytosis, in the cytoplasm, it is involved in the translational control of gene expression, in the nucleus, it functions in nuclear tRNA export, in DNA replication, and in DNA repair.Synonyms: CDABP0047, GAPD, Glyceraldehyde-3-Phosphate Dehydrogenase
Gene ID 2597
UniProt P04406
Research Area Cancer, Metabolism, Alzheimer's Disease, Enzymes
Application Notes ELISA. Western blot (1: 500 - 1: 10,000). Immunofluorescence (1: 500 - 1: 10,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, 0.09 % Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody (2) anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody (Image 2)
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody (3) anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody (Image 3)
anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody (4) anti-Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) (AA 1-335), (N-Term) antibody (Image 4)
Background publications Mazzola, Sirover: "Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders?" in: Neurotoxicology, Vol. 23, Issue 4-5, pp. 603-9, 2002 (PubMed).

Chuang, Hough, Senatorov: "Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases." in: Annual review of pharmacology and toxicology, Vol. 45, pp. 269-90, 2005 (PubMed).

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