Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
CATE antibody, A430072O03Rik antibody, C920004C08Rik antibody, CE antibody, CatE antibody, CEA antibody, CEB antibody, Ctsea antibody, CTSE antibody, ce1 antibody, ce2 antibody, cate antibody, CE1 antibody, ce1-A antibody, ctse antibody, CE2 antibody, ce2-A antibody, cathepsin E antibody, cathepsin E L homeolog antibody, cathepsin E S homeolog antibody, CTSE antibody, Ctse antibody, TP03_0056 antibody, Smp_184930 antibody, ctse antibody, ctse.L antibody, ctse.S antibody
Background
Cathepsin E is an intracellular aspartic protease of the pepsin family, which is structurally highly homologous to the lysosomal aspartic protease cathepsin D. Cathepsin E is less abundant than Cathepsin D and has a more limited distribution, which includes lymphoid tissues, gastrointestinal tract tissue, blood cells, microglia and activated B lymphocytes. It is not expressed in resting B lymphocytes.Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. It may also play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.Synonyms: CTSE